Phenotype Image Detail

Image

Caption

Immunofluorescence staining of the ventral horn of the spinal cord for Iba1 (microglia; red) and GFAP (astrocytes; green) of Tg(CAG-lacZ,-FUS,-EGFP)629Gyu/0 Meox2^tm1(cre)Sor/Meox2⁺ (CAG-FUS^WT) and Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu/0 Meox2^tm1(cre)Sor/Meox2⁺ (CAG-FUS^R521G) end-stage mice. Images are representative of three animals per genotype.

Copyright

This image is from Sephton CF, Proc Natl Acad Sci U S A 2014 Nov 4;111(44):E4769-78. Copyright 2014 National Academy of Sciences, U.S.A. J:216672

Associated Alleles

Symbol	Name
Meox2^tm1(cre)Sor	mesenchyme homeobox 2; targeted mutation 1, Philippe Soriano
Tg(CAG-lacZ,-FUS,-EGFP)629Gyu	transgene insertion 629, Gang Yu
Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu	transgene insertion 682, Gang Yu

Associated Genotypes

Allelic Composition	Genetic Background
Meox2^tm1(cre)Sor/Meox2^+ Tg(CAG-lacZ,-FUS,-EGFP)629Gyu/0	involves: 129S4/SvJaeSor * C57BL/6
Meox2^tm1(cre)Sor/Meox2^+ Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu/0	involves: 129S4/SvJaeSor * C57BL/6