Phenotype Image Detail

Image

Caption

Time course of central nervous system (CNS) vacuolation in Sox10^gt/Sox10^gt (gt/gt) mice. H&E stained paraffin sections of the pons (a), cerebellum (b) and thalamus (c) of mutant and wild-type mice at postnatal day 9 (P9), P10, P12 and P15. Vacuoles first appear in the pons and cerebellar white matter on P9, and in the thalamus between P10 and P12. In all brain regions, vacuoles become more numerous and larger with age. All panels at same magnification, scale bars 10 um.

Copyright

This image is from Anderson SR, Mamm Genome 2014 Nov 16;(): and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:216967

Associated Alleles

Symbol	Name
Sox10^gt	SRY (sex determining region Y)-box 10; gray tremor

Associated Genotypes

Allelic Composition	Genetic Background
Sox10^gt/Sox10^gt	GT/Le