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Phenotype Image Detail
Image
Caption Histological sections of epididmyal white adipose tissue (EWAT) from control (L/L) and Fitm2tm1.1DlsFitm2tm1.1Dls Tg(Fabp4-cre)1Rev/? (AF2KO) mice stained with H&E or immunolocalization of F4/80. The sections shown for H&E and F4/80 are non-consecutive. Adipose tissue macrophage infiltration, as indicated by the crownlike structures surrounding adipocytes, was observed in mutants.
Copyright This image is from Miranda DA, J Biol Chem 2014 Apr 4;289(14):9560-72 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:212437
Associated
Alleles
Symbol Name
Fitm2tm1.1Dls fat storage-inducing transmembrane protein 2; targeted mutation 1.1, David L Silver
Lepob leptin; obese
Associated
Genotypes
Allelic Composition Genetic Background
Fitm2tm1.1Dls/Fitm2tm1.1Dls
Tg(Fabp4-cre)1Rev/? 		involves: 129S6/SvEvTac * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory