Phenotype Image Detail

Image

Caption

Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/? (AF2KO) mice have reduced accumulation of adipose tissue in response to high fat diet. Images from MRI analysis of living mice indicate reduced amounts of subcutaneous white adipose tissue (SWAT) and epididmyal white adipose tissue (EWAT) in Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/? mice.

Copyright

This image is from Miranda DA, J Biol Chem 2014 Apr 4;289(14):9560-72 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:212437

Associated Alleles

Symbol	Name
Fitm2^tm1.1Dls	fat storage-inducing transmembrane protein 2; targeted mutation 1.1, David L Silver

Associated Genotypes

Allelic Composition	Genetic Background
Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/?	involves: 129S6/SvEvTac * C57BL/6J