Phenotype Image Detail

Image

Caption

(A) Gross morphology of E10.5 yolk sac and embryos of control and Bmp10^tm1Shou/Bmp10^tm1Shou. (B) Paraffin section of E9.5 embryos stained with PECAM-1 for blood vessels. Embryos show absent vitelline vessels in the yolk sac, stalled vascular development at the primary capillary plexus stage, and arteriovenous malformation (AVM).

Copyright

This image is from Chen H, Proc Natl Acad Sci U S A 2013 Jul 16;110(29):11887-92. Copyright 2013 National Academy of Sciences, U.S.A. J:222016

Associated Alleles

Symbol	Name
Bmp10^tm1Shou	bone morphogenetic protein 10; targeted mutation 1, Weinian Shou

Associated Genotypes

Allelic Composition	Genetic Background
Bmp10^tm1Shou/Bmp10^tm1Shou	involves: 129S/SvEv