Phenotype Image Detail

Image

Caption

Large autofluorescent particles in Zfyve26^tm1.1Cahb/Zfyve26^tm1.1Cahb (KO) tissues are Lamp1-positive. Confocal microscopy of cerebellar sections of 10-month-old mice. (A, B, C, D) Maximum intensity projections of all channels analyzed. (A-B"') Autofluorescent deposits (green) in Purkinje cells barely colocalized with EEA1 (red). (C-D"') Autofluorescent deposits in KO tissues were Lamp1-positive (clone CD107a). Scale bars: 10 um.

Copyright

This image is from Khundadze M, PLoS Genet 2013;9(12):e1003988, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223127

Associated Alleles

Symbol	Name
Zfyve26^tm1.1Cahb	zinc finger, FYVE domain containing 26; targeted mutation 1.1, Christian A Hubner

Associated Genotypes

Allelic Composition	Genetic Background
Zfyve26^tm1.1Cahb/Zfyve26^tm1.1Cahb	involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6