Phenotype Image Detail

Image

Caption

Reduced 3D-determined bone volume relative to tissue volume (3D-BV/TV) and microstructural derangements, by microCT scanning, in Cthrc1^tm1.1Suna/Cthrc1^tm1.1Suna Ctsk^tm1(cre)Ska/Ctsk⁺ (deltaOC) versus control (Ctr) mice. Representative 3D images of proximal tibia are shown. Scale bars: 1 mm. n = 5.

Copyright

This image is from Takeshita S, J Clin Invest 2013 Sep 3;123(9):3914-24 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201631

Associated Alleles

Symbol	Name
Cthrc1^tm1.1Suna	collagen triple helix repeat containing 1; targeted mutation 1.1, Sunao Takeshita
Ctsk^tm1(cre)Ska	cathepsin K; targeted mutation 1, Shigeaki Kato

Associated Genotypes

Allelic Composition	Genetic Background
Cthrc1^tm1.1Suna/Cthrc1^tm1.1Suna Ctsk^tm1(cre)Ska/Ctsk^+	involves: 129S6/SvEvTac * C57BL/6NCrlj * C57BL/6NTac * CBA/JNCrlj