Phenotype Image Detail

Image

Caption

Deletion of EHD4 leads to an increase in PCNA-positive cells at d10. Testis sections from d10, d20, and d31 wild-type (WT, Ehd^+/+) and Ehd4^tm1.1Haba/Ehd4^tm1.1Haba (Ehd4^-/-) male mice were subjected to PCNA staining. Panel (a), (e), and (g) represent 20X objective light microscope images of PCNA staining from d10, d20, and d31 WT testis, respectively, while panels (c), (f) and (h) represent images from d10, d20, and d31 mutant testis, respectively. Insets (b) and (d) represent 40X objective light microscope images. The seminiferous tubule diameter is indicated using the two-headed arows in panels g and h.

Copyright

This image is from George M, Genesis 2010 May;48(5):328-42, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:160188

Associated Alleles

Symbol	Name
Ehd4^tm1.1Haba	EH-domain containing 4; targeted mutation 1.1, Hamid Band

Associated Genotypes

Allelic Composition	Genetic Background
Ehd4^tm1.1Haba/Ehd4^tm1.1Haba	involves: C57BL/6 * C57BL/6J * FVB/N