Phenotype Image Detail

Image

Caption

Ikbkg^tm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 mice are sensitive to low doses of TRAIL-mediated liver injury. H&E staining (B) and TUNEL assay (C) showed tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated liver damage and apoptosis in Ikbkg^tm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0 (NEMO^deltahepa) mice.

Copyright

This image is from Beraza N, J Exp Med 2009 Aug 3;206(8):1727-37, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:151485

Associated Alleles

Symbol	Name
Ikbkg^tm1.1Chtr	inhibitor of kappaB kinase gamma; targeted mutation 1.1, Christian Trautwein
Tg(Alb1-cre)7Gsc	transgene insertion 7, Gunther Schutz

Associated Genotypes

Allelic Composition	Genetic Background
Ikbkg^tm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0	involves: C57BL/6 * FVB/N * SJL
Ikbkg^tm1.1Chtr/Y Tg(Alb1-cre)7Gsc/0	involves: C57BL/6 * FVB/N