Phenotype Image Detail

Image

Caption

(F, top) Electron microscopy photographs of renal glomeruli with increased mesangium and immunoglobulin deposition in Trim21^tm1Mwah/Trim21^tm1Mwah (Ro52-/-) mice indicated by arrows. Bar, 2 um. (F, bottom) Immunofluorescence IgG staining of renal glomeruli visualizing deposited IgG (red) and proteinuria (g/liter) in mice with dermatitis Ro52-/- (n = 7) and age-matched wild-type (Ro52+/+) mice (n = 8; mean +/- SEM; Mann-Whitney U test). Bar, 10 um.

Copyright

This image is from Espinosa A, J Exp Med 2009 Aug 3;206(8):1661-71, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:151775

Associated Alleles

Symbol	Name
Trim21^tm1Mwah	tripartite motif-containing 21; targeted mutation 1, Marie Wahren-Herlenius

Associated Genotypes

Allelic Composition	Genetic Background
Trim21^tm1Mwah/Trim21^tm1Mwah	C57BL/6-Trim21^tm1Mwah