Phenotype Image Detail

Image

Caption

Morphology of diaphragms from wild-type (WT), Fgfrl1^tm2.1True/Fgfrl1^tm2.1True (ki) and Fgfrl1^tm1True/Fgfrl1^tm1True (ko) mice were compared at E18.5. Coronal sections of the costal muscles stained with H&E are depicted below the panels showing overall morphology. Diaphragms from WT and knock-in mice did not reveal any differences. However, the diaphragms from knock-out animals were smaller and significantly thinner. Bar = 100 um.

Copyright

This image is from Bluteau G, PLoS One 2014;9(8):e105210, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:218981

Associated Alleles

Symbol	Name
Fgfrl1^tm1True	fibroblast growth factor receptor-like 1; targeted mutation 1, Beat Trueb
Fgfrl1^tm2.1True	fibroblast growth factor receptor-like 1; targeted mutation 2.1, Beat Trueb

Associated Genotypes

Allelic Composition	Genetic Background
Fgfrl1^tm1True/Fgfrl1^tm1True	B6.129S6-Fgfrl1^tm1True
Fgfrl1^tm2.1True/Fgfrl1^tm2.1True	B6.Cg-Fgfrl1^tm2.1True