Phenotype Image Detail

Image

Caption

Impaired lipid absorption in Neurog3^tm1Fgu/Neurog3^tm3.1Ggr Tg(Vil1-cre)20Syr/0 and Neurog3^tm3.1Ggr/Neurog3^tm3.1Ggr Tg(Vil1-cre)20Syr/0 (mutant) mice. Oil red O, which stains neutral fats, was used to visualize lipid droplets in control (A) and mutant (B) tissue. Mutant small intestine clearly shows a strong reduction in the amount of lipid droplets (dark dots in A and indicated by some flashes) compared to control tissue.

Copyright

This image is from Mellitzer G, J Clin Invest 2010 May 3;120(5):1708-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:161480

Associated Alleles

Symbol	Name
Neurog3^tm1Fgu	neurogenin 3; targeted mutation 1, Francois Guillemot
Neurog3^tm3.1Ggr	neurogenin 3; targeted mutation 3.1, Gerard Gradwohl
Tg(Vil1-cre)20Syr	transgene insertion 20, Sylvie Robine

Associated Genotypes

Allelic Composition	Genetic Background
Neurog3^tm1Fgu/Neurog3^tm3.1Ggr Tg(Vil1-cre)20Syr/0	involves: 129S2/SvPas * C57BL/6 * CD-1 * DBA/2 * SJL
Neurog3^tm3.1Ggr/Neurog3^tm3.1Ggr Tg(Vil1-cre)20Syr/0	involves: 129S2/SvPas * C57BL/6 * CD-1 * DBA/2 * SJL