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Caption | The combined loss of PTEN and Stk11 (Lkb1) induces bladder epithelium hyperproliferation. A, Immunohistochemical staining with anti-Ki67 antibody showing proliferative cells in the bladder epithelium of wild-type (WT), Ptentm2Mak/Ptentm2Mak Tg(Cyp1a1-cre/ERT)1Dwi/0 (Ptenfl/fl), Stk11tm1Keis/Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi/0 (Lkb1fl/fl), and Ptentm2Mak/Ptentm2Mak Stk11tm1Keis/Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi/0 (Cre+ Lkb1fl/fl Ptenfl/fl) mice (day 50 for all four genotypes and both days 50 and 125 for double-negatives. | ||||||||
Copyright | This image is from Shorning BY, PLoS One 2011;6(1):e16209, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:169565 | ||||||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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