Phenotype Image Detail

Image

Caption

Decreased bone development at muscle insertion sites. The deltoid tuberosity (arrows in Upper) and greater trochanter (arrows un Lower) of the femur are severely underdeveloped in Stac3^{tm1a(KOMP)Wtsi}/Stac3^{tm1a(KOMP)Wtsi} (KO) mice, suggesting lack of fetal muscle contraction. Remaining cervical and scapular fat tissue is also visible in the mutants.

Copyright

This image is from Nelson BR, Proc Natl Acad Sci U S A 2013 Jul 16;110(29):11881-6. Copyright 2013 National Academy of Sciences, U.S.A. J:222015

Associated Alleles

Symbol	Name
Stac3^tm1a(KOMP)Wtsi	SH3 and cysteine rich domain 3; targeted mutation 1a, Wellcome Trust Sanger Institute
Stac3^tm1a(KOMP)Wtsi	SH3 and cysteine rich domain 3; targeted mutation 1a, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Stac3^tm1a(KOMP)Wtsi/Stac3^tm1a(KOMP)Wtsi	involves: C57BL/6N