Phenotype Image Detail

Image

Caption

Histological analyses of skeletal muscles in newborn Stac3^{tm1a(KOMP)Wtsi}/Stac3^{tm1a(KOMP)Wtsi} (-/-) mice and wild-type (+/+) littermates. A-H, Hematoxylin and eosin staining of diaphragm, tongue, tibialis anterior (TA), and extensor digitorum longus (EDL) muscles. Note the difference in the location of myonuclei between the two genotypes. I and J, Immunohistochemical staining of EDL muscle for myosin heavy chain protein (red) and nuclei (blue). Shown are representative images taken from matched areas. Scale bars = 50 um for micrographs A, B, I, and J. Scale bars = 25 um for micrographs C-H.

Copyright

This image is from Reinholt BM, PLoS One 2013;8(4):e62760, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200631

Associated Alleles

Symbol	Name
Stac3^tm1a(KOMP)Wtsi	SH3 and cysteine rich domain 3; targeted mutation 1a, Wellcome Trust Sanger Institute
Stac3^tm1a(KOMP)Wtsi	SH3 and cysteine rich domain 3; targeted mutation 1a, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Stac3^tm1a(KOMP)Wtsi/Stac3^tm1a(KOMP)Wtsi	B6(Cg)-Stac3^tm1a(KOMP)Wtsi