Phenotype Image Detail

Image

Caption

Diaminobenzidine (DAB)-enhanced Perls' iron staining of hippocampus and cerebellum of aged Ireb2^tm1.1Eal/Ireb2^tm1.1Eal (Irp2^-/-) and wild-type (WT) mice. Coronal sections of hippocampus (A) (slide 41) and cerebellum (B) (slide 58) used for quantification of iron in CA1 pyramidal neurons. Dotted boxes indicate the WT (6B-4) and the mutant (6A-3) mice used for DAB-enhanced Perls' staining in File S1 and File S2. Ages of male mice: WT, 65-71 weeks; mutant (Irp2^-/-), 46-53 weeks.

Copyright

This image is from Zumbrennen-Bullough KB, PLoS One 2014;9(6):e98072, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:217335

Associated Alleles

Symbol	Name
Ireb2^tm1.1Eal	iron responsive element binding protein 2; targeted mutation 1.1, Elizabeth A Leibold

Associated Genotypes

Allelic Composition	Genetic Background
Ireb2^tm1.1Eal/Ireb2^tm1.1Eal	B6J.129-Ireb2^tm1.1Eal