Phenotype Image Detail

Image

Caption

Rps7^Zma/Rps7⁺ mutants have pyknotic nuclei in the spinal cord. H&E stained sagittal sections through the spinal cord of E18.5 wild-type (Rsp7^+/+) (A, B) and Rps7^Zma/Rps7⁺ (Rps7^Zma/+) (C, D) embryos. Arrow in D indicates an example of a darkly stained, condensed nucleus characteristic of pyknotic nuclei observed throughout the Rps7^Zma/Rps7⁺ spinal cord. Anterior is oriented towards the top and posterior to the bottom of all images. Boxed regions in A, C define the respective areas shown at higher magnification in B, D. Abbreviations: vertebral column (V), spinal cord (SC). Scale bars = 100 um.

Copyright

This image is from Watkins-Chow DE, PLoS Genet 2013 Jan;9(1):e1003094, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195156

Associated Alleles

Symbol	Name
Rps7^Zma	ribosomal protein S7; zuma

Associated Genotypes

Allelic Composition	Genetic Background
Rps7^Zma/Rps7^+	involves: BALB/c * C3H/HeH * C57BL/6J