Phenotype Image Detail

Image

Caption

Comparison of claudin-4 localization pattern in Cldn8^tm1.1Jhou/Cldn8^tm1.1Jhou Tg(Aqp2-cre)1Dek/0 (CLDN8^fl/fl/Aqp2^Cre) collecting ducts. Arrows denote remnant claudin-4 tight junction strands in mutant kidneys (where longer exposure time was taken for the claudin-4 signal to be seen).

Copyright

This image is from Gong Y, Proc Natl Acad Sci U S A 2015 Apr 7;112(14):4340-5. Copyright 2015 National Academy of Sciences, U.S.A. J:220813

Associated Alleles

Symbol	Name
Cldn8^tm1.1Jhou	claudin 8; targeted mutation 1.1, Jianghui Hou
Tg(Aqp2-cre)1Dek	transgene insertion 1, Donald E Kohan

Associated Genotypes

Allelic Composition	Genetic Background
Cldn8^tm1.1Jhou/Cldn8^tm1.1Jhou Tg(Aqp2-cre)1Dek/0	B6.Cg-Cldn8^tm1.1Jhou Tg(Aqp2-cre)1Dek