Phenotype Image Detail

Image

Caption

(B) P3 pups, where the Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd can be easily detected, as they have black spots due to a melanin pigmentation defect. (C) The homozygote (white with black spots) is significantly smaller compared with its littermate (brown; heterozygote or wild-type).

Copyright

This image is from Stobdan T, Proc Natl Acad Sci U S A 2015 Aug 18;112(33):10425-30. Copyright 2015 National Academy of Sciences, U.S.A. J:226561

Associated Alleles

Symbol	Name
Ednrb^tm1.1Nrd	endothelin receptor type B; targeted mutation 1.1, Noah Druckenbrod

Associated Genotypes

Allelic Composition	Genetic Background
Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd	involves: 129S1/Sv * 129X1/SvJ * C57BL/6