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Caption | Tracheal malformation in Fstl1tm1.1Ning/Fstl1tm1.1Ning (-/-) mice. (A) Transverse sections of the middle portion of trachea from a wild-type (-/-) and two homozygous mice before (E18.5) and after breath (P0) showed an increase in the lumen diameter (asterisk), dispersion and discontinuity of cartilage ring (arrow), and disorganization of the epithelial layer in the mutants. (Scale bars, 100 um.) (B) Alcian blue staining revealed impaired banding pattern of tracheal C-ring cartilage in all mutant skeletal preparations (ventral views). (C). Sections stained with an antibody against type II collagen (arrows). (Scale bars, 100 um.) | ||||
Copyright | This image is from Geng Y, Proc Natl Acad Sci U S A 2011 Apr 26;108(17):7058-63. Copyright 2011 National Academy of Sciences, U.S.A. J:171347 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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