Phenotype Image Detail

Image

Caption

Reduced neuritic complexity of Tg(PDGFB-LRRK2*G2019S)340Djmo/0 dopaminergic neurons in vitro. A, Example of neuritic morphology of immunoreactive TH+ and MAP+ dopaminergic neurons in primary midbrain cultures derived from Tg(PDGFB-LRRK2*G2019S)340Djmo/0 mice (TG) and their non-transgenic (NTG) littermates at days-in-vitro 7. TH+ neuronal soma (arrows) and neurites (arrowheads) are indicated.

Copyright

This image is from Ramonet D, PLoS One 2011;6(4):e18568, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:171645

Associated Alleles

Symbol	Name
Tg(PDGFB-LRRK2*G2019S)340Djmo	transgene insertion 340, Darren Moore

Associated Genotypes

Allelic Composition	Genetic Background
Tg(PDGFB-LRRK2*G2019S)340Djmo/0	involves: C3H/HeJ * C57BL/6J