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Phenotype Image Detail
Image
Caption Autophagic vacuoles accumulate in neuronal soma and axonal proceses in Tg(PDGFB-LRRK2*G2019S)340Djmo/0 transgenic mice. Transmission electron microscopic images of cerebral cortex tissue from 17-26 month-old transgenic mice highlighting the accumulation of autophagic vacuoles (indicated by *) within (A-B) neuronal soma and (C-D) axonal processes. Nuclei (nuc), axons (ax) and normal mitochondria (m) are indicated. Scale bars: 1 um (A-D).
Copyright This image is from Ramonet D, PLoS One 2011;6(4):e18568, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:171645
Associated
Alleles
Symbol Name
Tg(PDGFB-LRRK2*G2019S)340Djmo transgene insertion 340, Darren Moore
Associated
Genotypes
Allelic Composition Genetic Background
Tg(PDGFB-LRRK2*G2019S)340Djmo/0 involves: C3H/HeJ * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory