Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

High-frequency loss of Notch1 heterozygosity in Notch1^tm4(cre)Rko/Notch1^tm2Rko (N1::Cre^HI/flox) causes embryonic lethality at E10.5 due to angiogenic remodeling defects. Scale bar represents 500 um.

This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829

Associated
Alleles

Symbol	Name
Notch1^tm2Rko	notch 1; targeted mutation 2, Raphael Kopan
Notch1^tm4(cre)Rko	notch 1; targeted mutation 4, Raphael Kopan

Associated
Genotypes

Allelic Composition	Genetic Background
Notch1^tm2Rko/Notch1^tm4(cre)Rko	involves: 129X1/SvJ * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24