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Caption | (C) H&E section of control spleen. (D) H&E section of Notch1tm2Rko/Notch1tm3(cre)Rko spleen. Mutant animals show reactive splenomegaly to the inflammation in the liver, featured by the marked expansion of the interfollicular compartments and extra-medullary hematopoiesis of granulocytic, erythrocytic and megakaryotic lineages. | ||||||
Copyright | This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829 | ||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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