Phenotype Image Detail

Image

Caption

(E) Light (top) and scanning electron (bottom) microphotographs of wild-type and Atg4b^{Gt(A029E06)Wrst}/Atg4b^{Gt(A029E06)Wrst} (Atg5-/-) inner ears. Representative images showing the absence of otoconia (right) or the presence of giant and abnormally shaped otoconial crystals (middle) in the utricle of Atg4b^{Gt(A029E06)Wrst}/Atg4b^{Gt(A029E06)Wrst} mice. Scale bars: 50 um (top), 10 um (bottom).

Copyright

This image is from Marino G, J Clin Invest 2010 Jul 1;120(7):2331-44 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:163712

Associated Alleles

Symbol	Name
Atg5^tm1Nmz	autophagy related 5; targeted mutation 1, Noboru Mizushima

Associated Genotypes

Allelic Composition	Genetic Background
Atg5^tm1Nmz/Atg5^tm1Nmz	involves: 129S1/Sv * 129X1/SvJ