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Phenotype Image Detail
Image
Caption High magnification fluorescent images of the pharyngeal arch region of E9.5-10.5 DAPI stained (a) wild-type and (b) Rdh10trex/Rdh10trex (trex) embryos. Arrowheads illustrate the abnormal size and shape of individual pharyngeal arches in each of the mutants identified in our screen. The third arch in mutants is severely reduced in size leaving only a rudimentary structure, which is fused distally with the second arch. Mutants also show complete agenesis of the 4th pharyngeal arch.
Copyright This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
Associated
Alleles
Symbol Name
Rdh10trex retinol dehydrogenase 10 (all-trans); trex
Associated
Genotypes
Allelic Composition Genetic Background
Rdh10trex/Rdh10trex involves: 129S1/Sv * C57BL/6 * FVB/NJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory