Phenotype Image Detail

Image

Caption

Mice homozygous for the nee mutation develop a form of lipodystrophy. Coronal slices obtained by MRI showing an absence of subcutaneous and visceral adipose tissue in Sh3pxd2b^nee/Sh3pxd2b^nee (nee) mice. With this pulse sequence, fat appears white and muscle and water appear gray or black. Images are from the same pair of 8-month-old female mice; littermate control is homozygous for the wild-type (WT) allele.

Copyright

This image is from Mao M, Mamm Genome 2009 Aug;20(8):462-75 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:153369

Associated Alleles

Symbol	Name
Sh3pxd2b^nee	SH3 and PX domains 2B; nose eyes ear

Associated Genotypes

Allelic Composition	Genetic Background
Sh3pxd2b^nee/Sh3pxd2b^nee	B10.Cg-H2^h4 Sh3pxd2b^nee/GrsrJ