Phenotype Image Detail

Image

Caption

Motile cilia of lateral wall in Pdcd6ip^tm1.2Adz/Pdcd6ip^tm1.2Adz (KO) brain show defective orientation. (a) 3D reconstruction of whole-mount scanning electron microscopy (SEM) images of wild-type (WT) (n = 3) and mutant (n = 3) lateral wall. Inset: the typical 9+2 axoneme structure is maintained in mutant cilia. Scale bar, 100 um. (b) Transmission electron microscopy (TEM) of the basal bodies in WT and mutant ependymal cells (n = 2). Arrows indicate orientation of the basal bodies. Scale bar, 500 nm.

Copyright

This image is from Campos Y, Nat Commun 2016 Jun 23;7():11876, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:238436

Associated Alleles

Symbol	Name
Pdcd6ip^tm1.2Adz	programmed cell death 6 interacting protein; targeted mutation 1.2, Alessandra d'Azzo

Associated Genotypes

Allelic Composition	Genetic Background
Pdcd6ip^tm1.2Adz/Pdcd6ip^tm1.2Adz	either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)