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Phenotype Image Detail
Image
Caption (a) Transmission electron microscopy (TEM) micrographs of cross-sections of the wild-type (WT) and Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz (KO) choroid plexus (CP). Arrows point to the abnormal blebbing of microvilli in the mutant CP. Scale bar, 0.5 um. (b) Whole-mount WT and mutant CP immunostained for CD9, a marker of the microvilli. Scale bar, 10 um. (c) TEM micrographs of mutant CP showing the mislocalization of the basal bodies in the mutant CP. Scale bar, 500 nm.
Copyright This image is from Campos Y, Nat Commun 2016 Jun 23;7():11876, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:238436
Associated
Alleles
Symbol Name
Pdcd6iptm1.2Adz programmed cell death 6 interacting protein; targeted mutation 1.2, Alessandra d'Azzo
Associated
Genotypes
Allelic Composition Genetic Background
Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory