Phenotype Image Detail

Image

Caption

Eomes^tm1Rob/Eomes^tm2.1Rob Edil3^{Tg(Sox2-cre)1Amc}/0 embryos fail to form the mesoderm cell layer and are blocked in gastrulation as shown by cross-sections of E7.5 embryos.

Copyright

This image is from Arnold SJ, Genesis 2009 Nov;47(11):775-81, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:154785

Associated Alleles

Symbol	Name
Edil3^Tg(Sox2-cre)1Amc	EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Eomes^tm1Rob	eomesodermin; targeted mutation 1, Elizabeth J Robertson
Eomes^tm2.1Rob	eomesodermin; targeted mutation 2.1, Elizabeth J Robertson

Associated Genotypes

Allelic Composition	Genetic Background
Eomes^tm1Rob/Eomes^tm2.1Rob Edil3^Tg(Sox2-cre)1Amc/Edil3^+	involves: 129S/SvEv * C57BL/6 * CBA