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| Caption | Ptentm1Hwu/Ptentm1Hwu Tg(Tyr-cre)1Lru/0 (HM) mice displayed hyperplasia of the submucosa plexus of the enteric nervous system (ENS). Transverse sections of P15 wild-type (WT) and mutant colons were immunostained with an antibody directed against TUJ1. Note that hyperplasia was observed in the HM submucosal and mucosal ENS plexus, but not in WT (black arrowhead). Red squares correspond to the high magnification pictures on the right of the figure. Note the invasion of the nerves in the submucosal part of the intestine. Scale bar, left: 50 um; scale bar, right: 20 um. | ||||||
| Copyright | This image is from Puig I, J Clin Invest 2009 Dec;119(12):3586-96 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:155110 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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