Phenotype Image Detail

Image

Caption

Skeletal phenotype of Id1^tm1Zhu/Id1^tm1Zhu (Id1-/-) and wild-type (WT) mice at 6 weeks of age. (A) Photograph of a representative mutant and WT mouse. (B) X-ray micro-radiographs of hindlimbs. White arrows indicate trabecular bone regions. (C) Representative micro-CT images of the femoral trabecular and cortical regions in WT and mutant mice. (D) Three-point bending tests for evaluating the mechanical strength of femurs from WT (n = 8) and mutant (n = 8) mice. The parameters measured include the bending moment and the bending rigidity (*P<0.05, **P<0.01). Error bars represent +/-S.E.M.

Copyright

This image is from Chan AS, PLoS One 2009;4(11):e7955, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155384

Associated Alleles

Symbol	Name
Id1^tm1Zhu	inhibitor of DNA binding 1, HLH protein; targeted mutation 1, Yuan Zhuang

Associated Genotypes

Allelic Composition	Genetic Background
Id1^tm1Zhu/Id1^tm1Zhu	involves: 129S1/Sv * C57BL/6