Phenotype Image Detail

Image

Caption

H&E staining of 18 month old Itm2b^tm2.1Ldad/Itm2b^tm2.1Ldad mice showing signs of melanosis in the meninges of olfactory bulb (a) and signs of mineralization in the thalamus (d). The remaining parenchyma of brain cortex and hippocampus (b), cerebellum (c) and spinal cord (e) show normal cellular structures.

Copyright

This image is from Giliberto L, PLoS One 2009;4(11):e7900, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155411

Associated Alleles

Symbol	Name
Itm2b^tm2.1Ldad	integral membrane protein 2B; targeted mutation 2.1, Luciano D'Adamio

Associated Genotypes

Allelic Composition	Genetic Background
Itm2b^tm2.1Ldad/Itm2b^tm2.1Ldad	B6.129-Itm2b^tm2.1Ldad