Phenotype Image Detail

Image

Caption

Photograph of 5-day old mice with various genotypes as indicated. Arrow indicates Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa (Paxx-/- Xlf-/-) double mutant mouse. Paxx+ genotype refers to a combination of wild-type and heterozygous mice.

Copyright

This image is from Balmus G, Genes Dev 2016 Oct 1;30(19):2152-2157, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:236776

Associated Alleles

Symbol	Name
Nhej1^tm1Fwa	non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt
Paxx^em1Spj	non-homologous end joining factor; endonuclease-mediated mutation 1, Stephen P Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa	involves: 129S6/SvEvTac * C57BL/6NTac