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Phenotype Image Detail
Image
Caption Defect of large lysosome formation revealed by LAMP-1 staining in Enpp2tm1Mmas/Enpp2tm1Mmas (Enpp2-/-) visceral endoderm (VE) cells. Confocal microscopic images of VE cells stained with anti-LAMP-1 antibody (red) and Alexa488-phalloidin (green) are shown. LAMP-1-positive lysosomes were smaller in mutant VE cells than in wild-type (WT) VE cells. Scale bar represents 6 um.
Copyright This image is from Koike S, J Biol Chem 2009 Nov 27;284(48):33561-70 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:156013
Associated
Alleles
Symbol Name
Enpp2tm1Mmas ectonucleotide pyrophosphatase/phosphodiesterase 2; targeted mutation 1, Masayuki Masu
Associated
Genotypes
Allelic Composition Genetic Background
Enpp2tm1Mmas/Enpp2tm1Mmas involves: 129P2/OlaHsd * C57BL/6N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
MGI 6.24 		The Jackson Laboratory