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Caption | Impaired lymphocyte egress in Lyve1tm1.1(EGFP/cre)Cys/Lyve1+ Sphk1tm2Cgh/Sphk1tm2Cgh Sphk2tm1.1Cgh/Sphk2tm1.1Cgh (Sphk delta) mice. (G and H) Immunohistochemical analysis of lymph nodes (G) and Peyer's patches (H) stained for LYVE-1 (brown) and CD3 (blue) or B220 (blue). LYVE-1+ sinuses in lymphatic mutant lymph nodescontained almost no lymphocytes and appeared collapsed (G). Mutant animals also showed a defciency of lymphocytes in intestinal lymphatic sinuses adjacent to and likely draining from Peyer's patches (H). | ||||||||
Copyright | This image is from Pham TH, J Exp Med 2010 Jan 18;207(1):17-27, S1-4, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:156826 | ||||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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