Image |
|
||||||||
Caption | Abnormal lymphatic vessel maturation in Lyve1tm1.1(EGFP/cre)Cys/Lyve1+ Sphk1tm2Cgh/Sphk1tm2Cgh Sphk2tm1.1Cgh/Sphk2tm1.1Cgh mice. (A) Confocal images showing lymphatic vessels stained with antibody against LYVE-1 in whole mount of mouse trachea. Arrowheads point to the jagged appearance of the lymphatic vessels in Lyve1tm1.1(EGFP/cre)Cys/Lyve1+ Sphk1tm2Cgh/Sphk1tm2Cgh Sphk2tm1.1Cgh/Sphk2tm1.1Cgh (Sphk delta) mice. (B) Confocal images showing the button-like pattern of VE-cadherin at endothelial cell-cell junctions of the diaphragm initial lymphatics. Arrowheads mark VE-cadherin+ buttons in the control and a corresponding junctional region in the mutant mice. White squares (top) indicate enlarged regions (bottom). Data are representative of six experiments (n = 6 mice). (C) VE-cadherin buttons per 1,000-um2 projected area of lymphatic for littermate control and mutant trachea (n = 3 mice per group). Bars show means SE. *, P < 0.05 (Student's t test). | ||||||||
Copyright | This image is from Pham TH, J Exp Med 2010 Jan 18;207(1):17-27, S1-4, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:156826 | ||||||||
Associated Alleles |
|
||||||||
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
![]() |
|