Phenotype Image Detail

Image

Caption

Histological assessment of the cerebrospinal fluid (CSF) pathway in p23-ST1/p23-ST1 mice. (A) Serial coronal brain sections with H&E staining from 6-month-old mutant (lower panel) and age-matched control mice (upper panel) revealed enlarged lateral and third ventricles in mutant mouse compared to the control mice. The sizes of the cerebral aqueduct and fourth ventricle of the mutant mice were similar to those of control mice. Scale bars = 500 um. (B) Histological analysis of the choroid plexus of mutant (lower panel) and control (upper panel) mice aged 24 months. Microscopically, no hypertrophy or tissue swelling of the choroid plexus of mutant mice was found. Representative pictures of three independent mice in each group are shown. Scale bars = 100 um.

Copyright

This image is from Lee MJ, PLoS One 2009;4(11):e7868, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158278

Associated Alleles

Symbol	Name
p23-ST1	p23-ST1

Associated Genotypes

Allelic Composition	Genetic Background
p23-ST1/p23-ST1	C57BL/6J-p23-ST1