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Phenotype Image Detail
Image
Caption Whole mounts of a representative E13.5 litter derived from mating Apctm1Tno/Apctm1Tno Ctnnb1+/Ctnnb1+ with ApcMin/Apc+ Ctnnb1tm4.1Wbm/Ctnnb1+ mice. N = total number of embryos recovered for the indicated genotypes. Genotypes are as follows: Apc+/fl (+/fl; Apc+/Apctm1Tno); Apcmin/fl (min/fl; ApcMin/Apctm1Tno); Apcmin/fl; Ctnnb1+/- (min/fl;ctnnb1+/-; ApcMin/Apctm1Tno Ctnnb1tm4.1Wbm/Ctnnb1+); Apc+/fl;Ctnnb1+/- (+/fl;ctnnb1+/-; Apc+/Apctm1Tno Ctnnb1tm4.1Wbm/Ctnnb1+).
Copyright This image is from Buchert M, PLoS Genet 2010 Jan;6(1):e1000816, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:156864
Associated
Alleles
Symbol Name
ApcMin APC, WNT signaling pathway regulator; multiple intestinal neoplasia
Apctm1Tno APC, WNT signaling pathway regulator; targeted mutation 1, Tetsuo Noda
Ctnnb1tm4.1Wbm catenin beta 1; targeted mutation 4.1, Walter Birchmeier
Associated
Genotypes
Allelic Composition Genetic Background
ApcMin/Apctm1Tno involves: 129 * 129S4/SvJae * C57BL/6
ApcMin/Apctm1Tno
Ctnnb1tm4.1Wbm/Ctnnb1+
involves: 129 * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory