Phenotype Image Detail

Image

Caption

Histological analysis of acute kidney injury in Cldn2^tm1Lex/Y mice. Representative images of PAS-stained wild-type (A-C) and Cldn2^tm1Lex/Y (D-F) kidneys 48 hours after ischemia-reperfusion injury. Panels A and D show low-power views (scale bars: 100 um); panels B and E show high-power views of the cortex; and panels C and F show high-power views of the outer medulla. Scale bars: 50 um.

Copyright

This image is from Pei L, J Clin Invest 2016 Jul 01;126(7):2509-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:237065

Associated Alleles

Symbol	Name
Cldn2^tm1Lex	claudin 2; targeted mutation 1, Lexicon Pharmaceuticals
Cldn2^tm1Lex	claudin 2; targeted mutation 1, Lexicon Pharmaceuticals

Associated Genotypes

Allelic Composition	Genetic Background
Cldn2^tm1Lex/Y	B6J.129S5-Cldn2^tm1Lex