Phenotype Image Detail

Image

Caption

Nf1^tm1Fcr/Nf1⁺ Tg(GFAP-cre)#Gtm/0 (Nf1+/-^GFAPCKO) mice develop prechiasmatic optic nerve and chiasmal gliomas. FF, Nf1^flox/flox. Magnification, 10X. (Scale bar, 100 um.)

Copyright

This image is from Banerjee S, Proc Natl Acad Sci U S A 2011 Sep 20;108(38):15996-6001. Copyright 2011 National Academy of Sciences, U.S.A. J:176586

Associated Alleles

Symbol	Name
Nf1^tm1Fcr	neurofibromin 1; targeted mutation 1, Fredrick Cancer Research and Development Center
Tg(GFAP-cre)#Gtm	transgene insertion #, David H Gutmann

Associated Genotypes

Allelic Composition	Genetic Background
Nf1^tm1Fcr/Nf1^+ Tg(GFAP-cre)#Gtm/0	involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA