Phenotype Image Detail

Image

Caption

In vivo polyspermy with Adam24^tm1Pmkf/Adam24^tm1Pmkf male mice. A-D: Fluorescent and (A'-D') Nomarski images of pronucleus stage embryos having three pronuclei (A, B) or two pronuclei (C, D). Arrowheads point to the pronuclei in each embryo. We found a significantly higher number of embryos with three pronuclei in females mated with testase Adam24^tm1Pmkf/Adam24^tm1Pmkf compared to females mated with wild-type littermates.

Copyright

This image is from Zhu GZ, Mol Reprod Dev 2009 Nov;76(11):1106-14, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:157046

Associated Alleles

Symbol	Name
Adam24^tm1Pmkf	ADAM metallopeptidase domain 24; targeted mutation 1, Paul Primakoff

Associated Genotypes

Allelic Composition	Genetic Background
Adam24^tm1Pmkf/Adam24^tm1Pmkf	involves: C57BL/6J