Phenotype Image Detail

Image

Caption

Electron microscopy analysis of EDL muscle isolated from wild-type (WT) or Trdn^tm1.2Isma/Trdn^tm1.2Isma (KO) animals. EDL were isolated from WT or KO animals and examined using electron microscopy at different magnifications, with (a, c, and d) or without (b and e) tubule labeling. A number of triads are in abnormal orientation in KO muscle (white stars) and are presented mainly in a longitudinal orientation (c and d). The width of the terminal cisternae was measured as shown in b and e, respectively, on WT and KO muscles.

Copyright

This image is from Oddoux S, J Biol Chem 2009 Dec 11;284(50):34918-29 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:157794

Associated Alleles

Symbol	Name
Trdn^tm1.2Isma	triadin; targeted mutation 1.2, Isabelle Marty

Associated Genotypes

Allelic Composition	Genetic Background
Trdn^tm1.2Isma/Trdn^tm1.2Isma	involves: 129S2/SvPas * C57BL/6 * SJL