Phenotype Image Detail

Image

Caption

Defective liver development and anemia in Slc20a1^tm1.2Lbek/Slc20a1^tm1.2Lbek mice. (A-B) Comparison between wild-type (+/+) and Slc20a1^tm1.2Lbek/Slc20a1^tm1.2Lbek (delta5/delta5) embryos at E10.5 (A) and E12.5 (B). Note the reduced size, pale appearance and small liver (black arrow) of the E12.5 mutant embryos. (C, D) Haematoxilin and eosin (H&E) staining of E12.5 sections from wild-type (C) and mutant embryos (D). fl: fetal liver; mg: mid-gut loop; h: heart. Bar, 100 um. (E) Morphological appearance of wild-type and mutant E12.5 fetal livers. Bar, 0.5 mm.

Copyright

This image is from Beck L, PLoS One 2010;5(2):e9148, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:157997

Associated Alleles

Symbol	Name
Slc20a1^tm1.2Lbek	solute carrier family 20, member 1; targeted mutation 1.2, Laurent Beck

Associated Genotypes

Allelic Composition	Genetic Background
Slc20a1^tm1.2Lbek/Slc20a1^tm1.2Lbek	involves: 129S2/SvPas * BALB/c * C57BL/6 * C57BL/6J