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Phenotype Image Detail
Image
Caption Progressive loss of spiral ganglion neurons in Tmprss3m1Ingm/Tmprss3m1Ingm mice. (A): 12 days. Healthy appearing type I ganglion neurons. Note the myelin layer (arrow) and the body of a glial cell (g). n: nucleus of a ganglion neuron. (B): 4 months. Altered type I ganglion neuron showing an irregular shpaed nucleus, retracted cell body and disorganized mylein (arrows).
Copyright This image is from Fasquelle L, J Biol Chem 2011 May 13;286(19):17383-97 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:172676
Associated
Alleles
Symbol Name
Tmprss3m1Ingm transmembrane protease, serine 3; mutation 1, Ingenium Pharmaceuticals
Associated
Genotypes
Allelic Composition Genetic Background
Tmprss3m1Ingm/Tmprss3m1Ingm C3HeB/FeJ-Tmprss3m1Ingm
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory