Reference
Figure
ID
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J:240319
Stauber M, et al., Dev Biol. 2017 Mar 15;423(2):170-188
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MGI:6156363
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Caption | (A) Schematic view of a headfold stage mouse embryo (~E7.75; top) and of wildtype (wt), Noto-/- and Foxj1-/- mono-ciliated nodal cells (bottom). Cilia (green lines) in both Noto-/- and Foxj1-/- nodes are short and irregular and abnormally anchored to the cell cortex. Wildtype and residual Foxj1 expression is depicted by dark and light purple, respectively. The part of the embryo used in the screen is boxed in red. (B) Whole mount in situ hybridization on wildtype (a-d) and Noto null (e-h) embryos at early to late headfold stage (~E7.75-E8.0); a-h, view onto ventral node at the center of the images (cranial to the left); a', e', lateral view of node (arrow; dorsal view on same embryos as in a, e). (D) RT-PCR. M, DNA ladder; (-) control, cDNA synthesis without RNA; ~, 1700; H2O, PCR without primers as negative control; Hprt, PCR on a house keeping gene as positive control for the integrity of cDNA. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Copyright | Reprinted with permission from Elsevier from 10.1016/j.ydbio.2016.11.019 Dev Biol 423: 170-188, Stauber M; Weidemann M; Dittrich-Breiholz O; Lobschat K; Alten L; Mai M; Beckers A; Kracht M; Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Copyright 2017 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Associated Assays |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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