Phenotype Image Detail

Image

Caption

Loss of hair cells from Marveld2^tm1Sats/Marveld2^tm1Sats cochlea. (a) The organ of Corti of wild-type mice on P21 has one row of inner hair cells (IHCs) (arrowhead) and three rows of outer hair cells (OHCs) (arrows). (b) The stria vascularis and spiral ligament of wild-type mice. (c) IHCs (arrowhead) and OHCs (arrows) are frequently lost, but the spiral ganglion (SG) is intact in mutant mice. (d) Normal morphology of the stria vascularis (SV) and spiral ligament (SL) of mutant cochlea. Scale bar = 100 um.

Copyright

This image is from Kamitani T, Sci Rep 2015 Dec 18;5():18402, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:261357

Associated Alleles

Symbol	Name
Marveld2^tm1Sats	MARVEL (membrane-associating) domain containing 2; targeted mutation 1, Sachiko Tsukita

Associated Genotypes

Allelic Composition	Genetic Background
Marveld2^tm1Sats/Marveld2^tm1Sats	B6.Cg-Marveld2^tm1Sats