Phenotype Image Detail

Image

Caption

Developmental defects of the eye lids and oral cavity in Fbxw7^tm1.1Iken/Fbxw7⁺ mice. (A-D) Gross appearance (A, B) and H&E staining (C, D) of the wild-type (WT) (A, C) and mutant (B, D) mice. Bar, 5 mm (A, B); 500 um (C, D). Eyes open at birth (EOB) phenotype observed in mutant mice (B and D) but not in WT mice (A and C). (E, F) H&E staining of a mutant mouse showing cleft palate (F). Normal palate appearance was observed in WT mice (E). Bar, 500 um.

Copyright

This image is from Ikenoue T, Sci Rep 2018 Jan 31;8(1):2021, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:258194

Associated Alleles

Symbol	Name
Fbxw7^tm1.1Iken	F-box and WD-40 domain protein 7; targeted mutation 1.1, Tsuneo Ikenoue