Phenotype Image Detail

Image

Caption

General and heart phenotype of Hspb7^tm1.1Chen/Hspb7^tm1.1Chen Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ mice. (C) Hematoxylin and eosin (H&E) images of E11.5 control and Hspb7^tm1.1Chen/Hspb7^tm1.1Chen Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ (cKO (Nkx2.5-Cre)) embryos acquired using NanoZoomer slide scanner. (Scale bar: 0.5 mm.) Estimated location of sectioning is indicated by a dotted line on the whole-mount embryos images to the left. (Scale bar: 1 mm.) Magnified right ventricle (RV; red box) and left ventricle (LV; green box) wall views are shown to the right. Left and right ventricle wall thicknesses are indicated by rulers. (Scale bar: 0.1 mm.)

Copyright

This image is from Wu T, Proc Natl Acad Sci U S A 2017 Nov 7;114(45):11956-11961. Copyright 2017 National Academy of Sciences, U.S.A. J:256653

Associated Alleles

Symbol	Name
Hspb7^tm1.1Chen	heat shock protein family, member 7 (cardiovascular); targeted mutation 1.1, Ju Chen
Nkx2-5^tm1(cre)Rjs	NK2 homeobox 5; targeted mutation 1, Robert J Schwartz

Associated Genotypes

Allelic Composition	Genetic Background
Hspb7^tm1.1Chen/Hspb7^tm1.1Chen Nkx2-5^tm1(cre)Rjs/Nkx2-5^+	involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6