Phenotype Image Detail

Image

Caption

X-ray and skeletal staining with alizarin red of 5 month old wild-type (Col12a1+/+) and Col12a1^tm1Debi/Col12a1^tm1Debi (Col12a1-/-) mice. Col12a1^tm1Debi/Col12a1^tm1Debi mice demonstrated kyphosis (asterisk) in the x-ray image. Abnormal double spinous processes (arrows) were present in the vertebral column of mutant mice visualized by skeletal staining. L3, third lumbar.

Copyright

This image is from Izu Y, J Cell Biol 2011 Jun 13;193(6):1115-30, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:174217

Associated Alleles

Symbol	Name
Col12a1^tm1Debi	collagen, type XII, alpha 1; targeted mutation 1, David E Birk

Associated Genotypes

Allelic Composition	Genetic Background
Col12a1^tm1Debi/Col12a1^tm1Debi	involves: 129 * C57BL/6